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Drug Development for Dermatology

Dermatology is the branch of medicine dealing with the skin, nails, hair, and its diseases. The skin comprises the body’s largest organ and performs a variety of vital functions. It allows for temperature regulation, prevents dehydration, facilitates touch, temperature, and pain sensations, and even makes Vitamin D when we go out in the sun.

The skin protects the rest of the body from microbes, dirt, and even some chemicals. Since the skin is such a highly effective barrier, it makes the treatment of skin disorders and the delivery of drugs through the skin especially challenging.

Beyond formulation development considerations, pharmacokinetic and pharmacodynamic studies of dermatological drugs require specialized sampling methods, because many drugs designed to treat dermatological disorders are applied topically and do not enter the systemic circulation/bloodstream in appreciable quantities.

For transdermally delivered drugs, in which systemic exposure does occur, pharmacokinetic studies must be carefully planned to account for the long and variable absorption phases and must consider the potential safety implications of variable exposure at the site of administration versus the rest of the body.

Nuventra’s Dermatology Experience

Nuventra can perform any of our wide range of services for drugs to treat Dermatology indications. Some of our recent project experience in this area includes:

Visit our services page to see our full range of services and to learn more about what our drug development consultants can offer your program.

Dermatology Indications

Nuventra has experience with a number of dermatology indications, including:

  • Acne
  • Actinic Keratosis
  • Antifungal Infections
  • Atopic Dermatitis
  • Chronic Hand Eczema
  • Contact Dermatitis
  • Epilepsy (Transdermal)
  • Hyperhidrosis
  • Osteoarthritis (Transdermal)
  • Post Herpetic Neuralgia (Transdermal)
  • Psoriasis
  • Rosacea


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Drug Development for Dermatology

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