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Webinar | Allometric Scaling: Common Misconceptions During Drug Development

This webinar covers an introduction to allometric scaling, which is one of the tools that drug developers use to predict human pharmacokinetic (PK) data based on extrapolating animal data. Prediction methods, like allometric scaling, provide a “sneak peek” at how a drug might behave in humans before any clinical studies are conducted and can be used to help determine the right dose.

At the end of this webinar attendees should have a better understanding of:

  • Allometry and the nature of allometric exponents
  • Dose projection based on the predicted PK parameters in humans
  • Appropriate application of the allometric exponents to improve the prediction of PK parameters in humans from animal PK

Meet the Speaker

Iftekhar Mahmood, Ph.D.
Senior Consultant, Clinical Pharmacology and Pharmacometrics

Dr. Mahmood has more than 25 years of experience in clinical pharmacology with the FDA. He worked both in the Center for Drug Evaluation and Research (CDER) and the Center for Biologics Evaluation and Research (CBER). At the FDA, besides his review duties, Dr. Mahmood was involved with clinical pharmacology research (both small and large molecules) and published more than 100 research papers in peer-reviewed scientific journals. His research mainly focused on allometric scaling, modeling, sparse sampling, and pediatric drug development.

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